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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF4
All Species:
22.42
Human Site:
T208
Identified Species:
32.89
UniProt:
O43172
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43172
NP_004688.2
522
58449
T208
E
I
P
E
T
T
R
T
S
Q
M
Q
E
L
H
Chimpanzee
Pan troglodytes
XP_520198
559
62217
T245
E
I
P
E
T
T
R
T
S
Q
M
Q
E
L
H
Rhesus Macaque
Macaca mulatta
XP_001102859
521
58408
T207
E
I
P
E
T
T
R
T
S
Q
M
Q
E
L
H
Dog
Lupus familis
XP_532038
521
58332
T207
E
I
P
E
T
T
R
T
S
Q
M
Q
E
L
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9DAW6
521
58352
T207
E
I
P
E
T
T
R
T
S
Q
M
Q
E
L
H
Rat
Rattus norvegicus
Q5BK30
415
45841
C106
A
L
N
K
A
G
S
C
F
I
T
G
S
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518220
390
43930
E81
S
R
T
S
Q
K
Q
E
L
H
K
A
L
R
S
Chicken
Gallus gallus
Q5ZMA2
505
55116
K192
T
E
R
K
K
R
G
K
T
V
P
E
E
L
V
Frog
Xenopus laevis
Q5FWQ6
415
45899
S106
A
F
N
K
S
G
S
S
F
I
T
G
S
Y
D
Zebra Danio
Brachydanio rerio
Q1LV15
415
45916
C106
A
F
N
K
S
G
S
C
F
I
T
G
S
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KNS3
411
46441
K101
W
I
P
R
P
P
E
K
F
S
L
T
G
H
R
Honey Bee
Apis mellifera
XP_393186
525
59172
T201
E
L
P
T
A
T
R
T
A
R
R
Q
E
L
L
Nematode Worm
Caenorhab. elegans
Q10051
492
53189
N183
E
R
K
Q
R
G
K
N
L
P
E
G
L
A
K
Sea Urchin
Strong. purpuratus
XP_795434
502
56264
N188
K
I
P
E
S
Q
T
N
A
R
R
Q
E
L
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O22212
554
61823
R224
I
Q
R
A
K
R
R
R
D
D
P
D
E
D
M
Baker's Yeast
Sacchar. cerevisiae
P20053
465
52424
R156
R
Q
E
L
L
S
R
R
T
E
L
Q
R
M
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.8
99
99.2
N.A.
98.8
25.4
N.A.
71.2
21
24.1
24.3
N.A.
22.2
58.2
22
62
Protein Similarity:
100
93.1
99.2
99.6
N.A.
99.4
40.6
N.A.
73.3
41.3
41.3
41.5
N.A.
39.6
72.9
40.6
77
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
0
13.3
0
0
N.A.
13.3
53.3
6.6
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
13.3
N.A.
6.6
33.3
20
13.3
N.A.
20
73.3
20
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
40
31.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55.7
51.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
19
0
0
7
13
0
0
0
13
0
0
7
0
7
7
% A
% Cys:
0
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
7
7
0
7
0
7
19
% D
% Glu:
44
7
7
38
0
0
7
7
0
7
7
7
57
0
0
% E
% Phe:
0
13
0
0
0
0
0
0
25
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
25
7
0
0
0
0
25
7
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
0
0
7
38
% H
% Ile:
7
44
0
0
0
0
0
0
0
19
0
0
0
0
0
% I
% Lys:
7
0
7
25
13
7
7
13
0
0
7
0
0
0
7
% K
% Leu:
0
13
0
7
7
0
0
0
13
0
13
0
13
50
7
% L
% Met:
0
0
0
0
0
0
0
0
0
0
32
0
0
7
7
% M
% Asn:
0
0
19
0
0
0
0
13
0
0
0
0
0
0
0
% N
% Pro:
0
0
50
0
7
7
0
0
0
7
13
0
0
0
0
% P
% Gln:
0
13
0
7
7
7
7
0
0
32
0
50
0
0
0
% Q
% Arg:
7
13
13
7
7
13
50
13
0
13
13
0
7
7
7
% R
% Ser:
7
0
0
7
19
7
19
7
32
7
0
0
19
0
7
% S
% Thr:
7
0
7
7
32
38
7
38
13
0
19
7
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
7
0
0
0
0
7
% V
% Trp:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _